MicroRNA-138 Overexpression Alters Aβ42 Levels and Behavior in Wildtype Mice

MicroRNA-138 Overexpression Alters Aβ42 Levels and Behavior in Wildtype Mice

Alzheimer’s disease (AD) is a progressive neurodegenerative disorder characterized by changes in cognitive and behavioral functions. With the exception or rare mutations in PSEN and APP genes causing early-onset autosomal dominant AD (EOADAD), little is known about the genetic factors that underlie...

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Bibliographic Details
Main Authors: Emmanuelle Boscher, Claudia Goupil, Serena Petry, Rémi Keraudren, Andréanne Loiselle, Emmanuel Planel, Sébastien S. Hébert
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-01-01
Series:Frontiers in Neuroscience
Subjects:
Alzheimer’s disease
microRNA
MiR-138
memory
anxiety
adeno-associated virus
Online Access:https://www.frontiersin.org/articles/10.3389/fnins.2020.591138/full

Internet

https://www.frontiersin.org/articles/10.3389/fnins.2020.591138/full

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