CD133 Targeted PVP/PMMA Microparticle Incorporating Levamisole for the Treatment of Ovarian Cancer

Levamisole (LEVA) is used to treat worm infections, but it can also inhibit cancer cell growth by inhibiting the aldehyde dehydrogenase pathway. Therefore, here, we developed a drug carrier targeting CD133, a biomarker overexpressed in ovarian cancer cells. The particle structure and cytotoxicity of...

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Bibliographic Details
Main Authors: Yu-Chi Wang, Meng-Yi Bai, Ying-Ting Yeh, Sung-Ling Tang, Mu-Hsien Yu
Format: Article
Language:English
Published: MDPI AG 2020-02-01
Series:Polymers
Subjects:
Online Access:https://www.mdpi.com/2073-4360/12/2/479