Transmigration of Neutrophils From Patients With Familial Mediterranean Fever Causes Increased Cell Activation

Transmigration of Neutrophils From Patients With Familial Mediterranean Fever Causes Increased Cell Activation

Familial Mediterranean fever (FMF) is caused by pyrin-encoding MEFV gene mutations and characterized by the self-limiting periods of intense inflammation, which are mainly mediated by a massive influx of polymorphonuclear neutrophils (PMNs) into the inflamed sites. Perturbation of actin polymerizati...

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Bibliographic Details
Main Authors: Anush Martirosyan, David Poghosyan, Susanna Ghonyan, Nune Mkrtchyan, Gayane Amaryan, Gayane Manukyan
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-05-01
Series:Frontiers in Immunology
Subjects:
Familial Mediterranean fever
neutrophils
fresh/aged neutrophils
transmigration
IL-1β
immunophenotype
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2021.672728/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2021.672728/full

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