Schizandrin Protects Primary Rat Cortical Cell Cultures from Glutamate-Induced Apoptosis by Inhibiting Activation of the MAPK Family and the Mitochondria Dependent Pathway

Schizandrin Protects Primary Rat Cortical Cell Cultures from Glutamate-Induced Apoptosis by Inhibiting Activation of the MAPK Family and the Mitochondria Dependent Pathway

Glutamate-induced excitotoxicity has been implicated in a variety of neuronal degenerative disorders. In the present study, we investigated the possible neuroprotective effects of schizandrin against apoptosis of primary cultured rat cortical cells induced by glutamate. Glutamate (10 μM...

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Bibliographic Details
Main Authors: Wen-Huang Peng, Ming-Tsuen Hsieh, Fan-Shiu Tsai, Li-Wei Lin, Jiin-Cherng Yen, Jung Chao, Meng-Shiou Lee, Hao-Yuan Cheng
Format: Article
Language:English
Published: MDPI AG 2012-12-01
Series:Molecules
Subjects:
glutamate
apoptosis
schizandrin
neuroprotection
Online Access:http://www.mdpi.com/1420-3049/18/1/354

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http://www.mdpi.com/1420-3049/18/1/354

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