Depletion of the SR-Related Protein TbRRM1 Leads to Cell Cycle Arrest and Apoptosis-Like Death in Trypanosoma brucei.

Arginine-Serine (RS) domain-containing proteins are RNA binding proteins with multiple functions in RNA metabolism. In mammalian cells this group of proteins is also implicated in regulation and coordination of cell cycle and apoptosis. In trypanosomes, an early branching group within the eukaryotic...

Full description

Bibliographic Details
Main Authors: Gabriela V Levy, Carolina P Bañuelos, Analía G Níttolo, Gastón E Ortiz, Nicolás Mendiondo, Georgina Moretti, Valeria S Tekiel, Daniel O Sánchez
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4540419?pdf=render