The anti-inflammatory drug leflunomide is an agonist of the aryl hydrocarbon receptor.

The anti-inflammatory drug leflunomide is an agonist of the aryl hydrocarbon receptor.

The aryl hydrocarbon receptor (AhR) is a ligand-activated transcription factor that mediates the toxicity and biological activity of dioxins and related chemicals. The AhR influences a variety of processes involved in cellular growth and differentiation, and recent studies have suggested that the Ah...

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Bibliographic Details
Main Authors: Edmond F O'Donnell, Katerine S Saili, Daniel C Koch, Prasad R Kopparapu, David Farrer, William H Bisson, Lijoy K Mathew, Sumitra Sengupta, Nancy I Kerkvliet, Robert L Tanguay, Siva Kumar Kolluri
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-10-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2948512?pdf=render

Internet

http://europepmc.org/articles/PMC2948512?pdf=render

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