Late effects of adjuvant chemotherapy adumbrate dormancy complexity in breast cancer

Background: Dormant avascular micrometastases and single, or small groups of, non-proliferating cells are currently assumed to explain the multipeak dynamics of distant metastases (DM) following primary breast cancer surgical removal. Methods: The hazard rate pattern for DM was analysed in 1518 prem...

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Bibliographic Details
Main Authors: Romano Demicheli, Christine Desmedt, Mike Retsky, Christos Sotiriou, Martine Piccart, Elia Biganzoli
Format: Article
Language:English
Published: Elsevier 2020-08-01
Series:Breast
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S0960977620301090