Overexpression of CDC42SE1 in A431 Cells Reduced Cell Proliferation by Inhibiting the Akt Pathway

Cell division cycle 42 (CDC42), a small Rho GTPase, plays a critical role in many cellular processes, including cell proliferation and survival. CDC42 interacts with the CRIB (Cdc42- and Rac-interactive binding) domain of CDC42SE1, a small effector protein of 9 kDa. We found that the expression of C...

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Bibliographic Details
Main Authors: Pazhanichamy Kalailingam, Hui Bing Tan, Jiun Yit Pan, Suat Hoon Tan, Thirumaran Thanabalu
Format: Article
Language:English
Published: MDPI AG 2019-02-01
Series:Cells
Subjects:
Online Access:https://www.mdpi.com/2073-4409/8/2/117