Four microRNAs promote prostate cell proliferation with regulation of PTEN and its downstream signals in vitro.

Phosphatase and tensin homologue (PTEN), as a tumor suppressor, plays vital roles in tumorigenesis and progression of prostate cancer. However, the mechanisms of PTEN regulation still need further investigation. We here report that a combination of four microRNAs (miR-19b, miR-23b, miR-26a and miR-9...

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Bibliographic Details
Main Authors: Ling Tian, Yu-xiang Fang, Jing-lun Xue, Jin-zhong Chen
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3787937?pdf=render