CRTH2 promotes endoplasmic reticulum stress‐induced cardiomyocyte apoptosis through m‐calpain

CRTH2 promotes endoplasmic reticulum stress‐induced cardiomyocyte apoptosis through m‐calpain

Abstract Apoptotic death of cardiac myocytes is associated with ischemic heart disease and chemotherapy‐induced cardiomyopathy. Chemoattractant receptor‐homologous molecule expressed on T helper type 2 cells (CRTH2) is highly expressed in the heart. However, its specific role in ischemic cardiomyopa...

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Bibliographic Details
Main Authors: Shengkai Zuo, Deping Kong, Chenyao Wang, Jiao Liu, Yuanyang Wang, Qiangyou Wan, Shuai Yan, Jian Zhang, Juan Tang, Qianqian Zhang, Luheng Lyu, Xin Li, Zhixin Shan, Li Qian, Yujun Shen, Ying Yu
Format: Article
Language:English
Published: Wiley 2018-03-01
Series:EMBO Molecular Medicine
Subjects:
calpain
cardiomyocyte apoptosis
CRTH2
endoplasmic reticulum stress
prostaglandin D2
Online Access:https://doi.org/10.15252/emmm.201708237

Internet

https://doi.org/10.15252/emmm.201708237

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