Ghrelin attenuates the osteoblastic differentiation of vascular smooth muscle cells through the ERK pathway.

Ghrelin attenuates the osteoblastic differentiation of vascular smooth muscle cells through the ERK pathway.

Vascular calcification results from osteoblastic differentiation of vascular smooth muscle cells (VSMCs) and is a major risk factor for cardiovascular events. Ghrelin is a newly discovered bioactive peptide that acts as a natural endogenous ligand of the growth hormone secretagog receptor (GHSR). Se...

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Bibliographic Details
Main Authors: Qiu-Hua Liang, Yi Jiang, Xiao Zhu, Rong-Rong Cui, Guan-Ying Liu, Yuan Liu, Shan-Shan Wu, Xiao-Bo Liao, Hui Xie, Hou-De Zhou, Xian-Ping Wu, Ling-Qing Yuan, Er-Yuan Liao
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3326017?pdf=render

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http://europepmc.org/articles/PMC3326017?pdf=render

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