Genetic polymorphism and their contribution to cancer susceptibility
Since the majority of chemical carcinogens are not capable of causing hazardous effects per se, the metabolism of these compounds is a crucial part of the initial host response to the environmental exposure. Disturbances in the balance between activation and detoxification may thus explain the indiv...
Main Authors: | , , |
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Format: | Article |
Language: | English |
Published: |
Escola Nacional de Saúde Pública, Fundação Oswaldo Cruz
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Series: | Cadernos de Saúde Pública |
Subjects: | |
Online Access: | http://www.scielosp.org/scielo.php?script=sci_arttext&pid=S0102-311X1998000700002&lng=en&tlng=en |