Extracellular vesicles from human mesenchymal stem cells expedite chondrogenesis in 3D human degenerative disc cell cultures

Extracellular vesicles from human mesenchymal stem cells expedite chondrogenesis in 3D human degenerative disc cell cultures

Abstract Background Extracellular vesicles (EVs) from human mesenchymal stem cells (hMSCs) are known to be mediators of intercellular communication and have been suggested as possible therapeutic agents in many diseases. Their potential use in intervertebral disc (IVD) degeneration associated with l...

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Bibliographic Details
Main Authors: Daphne Hingert, Karin Ekström, Jonathan Aldridge, Rosella Crescitelli, Helena Brisby
Format: Article
Language:English
Published: BMC 2020-07-01
Series:Stem Cell Research & Therapy
Subjects:
Extracellular vesicles
Exosomes
Human mesenchymal stem cells
Intervertebral disc cells
Low back pain
Chondrogenesis
Online Access:http://link.springer.com/article/10.1186/s13287-020-01832-2

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http://link.springer.com/article/10.1186/s13287-020-01832-2

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