Host Interferon-Gamma Inducible Protein Contributes to Brucella Survival

Host Interferon-Gamma Inducible Protein Contributes to Brucella Survival

Brucella spp. are highly adapted intracellular pathogens of mammals that cause chronic infections while surving and replicating in host monocytes and macrophages. Although monocytes are normally susceptible to infection, pretreatment with pro-inflammatory cytokine interferon- (IFN-) activates cell...

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Bibliographic Details
Main Authors: Jennifer eRitchie, Adam eRupper, James eCardelli, Bryan eBellaire
Format: Article
Language:English
Published: Frontiers Media S.A. 2012-04-01
Series:Frontiers in Cellular and Infection Microbiology
Subjects:
Brucella abortus
interferon gamma
Brucella pathogenesis
Chronic infection
differential internalization
Intracellular survival
Online Access:http://journal.frontiersin.org/Journal/10.3389/fcimb.2012.00055/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fcimb.2012.00055/full

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