Cdk11-CyclinL Controls the Assembly of the RNA Polymerase II Mediator Complex

The large Mediator (L-Mediator) is a general coactivator of RNA polymerase II transcription and is formed by the reversible association of the small Mediator (S-Mediator) and the kinase-module-harboring Cdk8. It is not known how the kinase module association/dissociation is regulated. We describe t...

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Bibliographic Details
Main Authors: Julie Drogat, Valérie Migeot, Elise Mommaerts, Caroline Mullier, Marc Dieu, Harm van Bakel, Damien Hermand
Format: Article
Language:English
Published: Elsevier 2012-11-01
Series:Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124712003312