Melanoma: Genetic Abnormalities, Tumor Progression, Clonal Evolution and Tumor Initiating Cells

Melanoma is an aggressive neoplasia issued from the malignant transformation of melanocytes, the pigment-generating cells of the skin. It is responsible for about 75% of deaths due to skin cancers. Melanoma is a phenotypically and molecularly heterogeneous disease: cutaneous, uveal, acral, and mucos...

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Bibliographic Details
Main Authors: Ugo Testa, Germana Castelli, Elvira Pelosi
Format: Article
Language:English
Published: MDPI AG 2017-11-01
Series:Medical Sciences
Subjects:
Online Access:https://www.mdpi.com/2076-3271/5/4/28