Smad4-mediated TGF-β signaling in tumorigenesis
<p>Transforming growth factor-β (TGF-β) family members exert their function via specific type I and type II serine/threonine kinase receptors and intracellular Smad transcription factors, including the common mediator Smad4. The dual effects of TGF-β signaling on tum...
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| Format: | Article |
| Language: | English |
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Ivyspring International Publisher
2010-01-01
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| Series: | International Journal of Biological Sciences |
| Online Access: | http://www.biolsci.org/v06p0001.htm |