Responsiveness of glycogen breakdown to cyclic AMP in perfused liver from rats with insulin-induced hypoglycemia

The responsiveness of glycogen breakdown to cAMP was investigated in isolated perfused liver from male Wistar fed rats (200-220 g) with insulin-induced hypoglycemia. The activation of glycogenolysis by 3 µM cAMP was decreased (P<0.05) in livers from rats with hypoglycemia induced by the administr...

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Bibliographic Details
Main Authors: M. Vardanega-Peicher, R. Curi, S. Pagliarini e Silva, K.F. Nascimento, R.B. Bazotte
Format: Article
Language:English
Published: Associação Brasileira de Divulgação Científica 2003-01-01
Series:Brazilian Journal of Medical and Biological Research
Subjects:
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2003000100007