Linking dopamine neurotransmission and neurogenesis: the evolutionary history of the NTAD (NCAM1-TTC12-ANKK1-DRD2) gene cluster

Linking dopamine neurotransmission and neurogenesis: the evolutionary history of the NTAD (NCAM1-TTC12-ANKK1-DRD2) gene cluster

Genetic studies have long suggested the important role of the DRD2 gene in psychiatric disorders and behavior. Further research has shown a conjoined effect of genes in the Chr11q22-23 region, which includes the NCAM1, TTC12, ANKK1 and DRD2 genes, or NTAD cluster. Despite a growing need to unravel t...

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Bibliographic Details
Main Authors: Nina Roth Mota, Eli Vieira Araujo-Jnr, Vanessa Rodrigues Paixão-Côrtes, Maria Cátira Bortolini, Claiton Henrique Dotto Bau
Format: Article
Language:English
Published: Sociedade Brasileira de Genética 2012-01-01
Series:Genetics and Molecular Biology
Subjects:
NTAD cluster
Taq1A SNP
shared synteny
co-regulation
psychiatric genetics
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1415-47572012000600004

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http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1415-47572012000600004

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