Regulation of neuronal cell death by c-Abl-Hippo/MST2 signaling pathway.

BACKGROUND: Mammalian Ste20-like kinases (MSTs) are the mammalian homologue of Drosophila hippo and play critical roles in regulation of cell death, organ size control, proliferation and tumorigenesis. MSTs exert pro-apoptotic function through cleavage, autophosphorylation and in turn phosphorylatio...

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Bibliographic Details
Main Authors: Weizhe Liu, Junbing Wu, Lei Xiao, Yujie Bai, Aiqin Qu, Zheng Zheng, Zengqiang Yuan
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3348883?pdf=render