Dissecting the Roles of Gonadotropin-Inhibitory Hormone in Mammals: Studies using Pharmacological Tools and Genetically Modified Mouse Models

Reproduction is essential for perpetuation of the species and, hence, is controlled by a sophisticated network of regulatory factors of central and peripheral origin that integrate at the hypothalamic-pituitary gonadal (HPG) axis. Among the central regulators of reproduction, kisspeptins, as major s...

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Bibliographic Details
Main Authors: Silvia eLeon, Manuel eTena-Sempere
Format: Article
Language:English
Published: Frontiers Media S.A. 2016-01-01
Series:Frontiers in Endocrinology
Subjects:
RF9
Online Access:http://journal.frontiersin.org/Journal/10.3389/fendo.2015.00189/full