Vaccinia virus regulates expression of p21WAF1/Cip1 in A431 cells

In this paper, we provide evidence that both the mRNA and protein levels of the cyclin-dependent kinase (CDK) inhibitor p21WAF1/CDK-interacting protein 1 (Cip1) increase upon infection of A431 cells with Vaccinia virus (VACV). In addition, the VACV growth factor (VGF) seems to be required for the ge...

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Bibliographic Details
Main Authors: Anderson A Andrade, Bruno SAF Brasil, Anna CTC Pereira, Paulo CP Ferreira, Erna G Kroon, Cláudio A Bonjardim
Format: Article
Language:English
Published: Instituto Oswaldo Cruz, Ministério da Saúde 2010-05-01
Series:Memórias do Instituto Oswaldo Cruz.
Subjects:
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02762010000300005