Hydantoins: Synthesis, properties and anticonvulsant activity

Hydantoins: Synthesis, properties and anticonvulsant activity

Hydantoin is a five-membered cyclic ureide that is present in numerous biologically active compounds including antiarrhytmics, anticonvulsants and antitumor agents. This paper describes different ways of synthesis of hydantoin-derivatives, their physical properties and reactivity. Also, the most wid...

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Bibliographic Details
Main Authors: Trišović Nemanja P., Ušćumlić Gordana S., Petrović Slobodan D.
Format: Article
Language:English
Published: Association of Chemical Engineers of Serbia 2009-01-01
Series:Hemijska Industrija
Subjects:
hydantoin
properties
reactivity
synthesis
phenytoin
anticonvulsant activity
pharmacofor model
lipophilicity
hydrogen bonding
Online Access:http://www.doiserbia.nb.rs/img/doi/0367-598X/2009/0367-598X0901017T.pdf

Internet

http://www.doiserbia.nb.rs/img/doi/0367-598X/2009/0367-598X0901017T.pdf

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