Bucindolol: A Pharmacogenomic Perspective on its Use in Chronic Heart Failure
Bucindolol is a non-selective β-adrenergic receptor blocker with α-1 blocker properties and mild intrinsic sympatholytic activity. The Beta-Blocker Evaluation of Survival Trial (BEST), which is the largest clinical trial of bucindolol in patients with heart failure, was terminated prematurely and fa...
Main Authors: | Neil A. Smart, Nigel Kwok, David J. Holland, Rohan Jayasighe, Francesco Giallauria |
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Format: | Article |
Language: | English |
Published: |
SAGE Publishing
2011-01-01
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Series: | Clinical Medicine Insights: Cardiology |
Online Access: | https://doi.org/10.4137/CMC.S4309 |
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