Bucindolol: A Pharmacogenomic Perspective on its Use in Chronic Heart Failure

Bucindolol is a non-selective β-adrenergic receptor blocker with α-1 blocker properties and mild intrinsic sympatholytic activity. The Beta-Blocker Evaluation of Survival Trial (BEST), which is the largest clinical trial of bucindolol in patients with heart failure, was terminated prematurely and fa...

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Bibliographic Details
Main Authors: Neil A. Smart, Nigel Kwok, David J. Holland, Rohan Jayasighe, Francesco Giallauria
Format: Article
Language:English
Published: SAGE Publishing 2011-01-01
Series:Clinical Medicine Insights: Cardiology
Online Access:https://doi.org/10.4137/CMC.S4309