Phase II Trial of Doxorubicin Plus Escalated High-Dose Ifosfamide in Patients With Advanced Soft Tissue Sarcomas of the Adult: A Study of the Spanish Group for Research on Sarcomas (GEIS)

Background. To explore the tolerance and the activity of high-dose ifosfamide (IFOS) combined with doxorubicin (DXR) at 50 mg/m2 every 4 weeks in patients with soft tissue sarcomas. Methods. DXR was given IV bolus and IFOS by continuous infusion at 2 g/m2/day. Initial IFOS dose (12 g/m2) was adjuste...

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Main Authors: A. López-Pousa, J. Martín, J. Montalar, R. de las Peñas, J. García del Muro, J. Cruz, J. Maurel, P. Escudero, A. Casado, J. M. Buesa, the Spanish Group for Research on Sarcomas (GEIS)
Format: Article
Language:English
Published: Hindawi Limited 2006-01-01
Series:Sarcoma
Online Access:http://dx.doi.org/10.1155/SRCM/2006/26986