Generation of murine macrophage-derived cell lines expressing porcine CD163 that support porcine reproductive and respiratory syndrome virus infection

Generation of murine macrophage-derived cell lines expressing porcine CD163 that support porcine reproductive and respiratory syndrome virus infection

Abstract Background Porcine reproductive and respiratory syndrome virus (PRRSV) exhibits a highly restricted tropism for cells of the monocyte-macrophage lineage, utilizing porcine CD163 (pCD163) as an indispensable cellular receptor for infection. Transfection the gene of pCD163 into several non-pe...

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Bibliographic Details
Main Authors: Liangliang Li, Chunyan Wu, Gaopeng Hou, Biyun Xue, Sha Xie, Qin Zhao, Yuchen Nan, Gaiping Zhang, En-Min Zhou
Format: Article
Language:English
Published: BMC 2017-11-01
Series:BMC Biotechnology
Subjects:
Murine macrophage-derived cells
Porcine CD163
PRRSV
Online Access:http://link.springer.com/article/10.1186/s12896-017-0399-5

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http://link.springer.com/article/10.1186/s12896-017-0399-5

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