Synthesis, Antibacterial and Pharmacokinetic Evaluation of Novel Derivatives of Harmine N<sup>9</sup>-Cinnamic Acid

A series of 16 new derivatives of harmine N<sup>9</sup>-Cinnamic acid were synthesized and fully characterized using NMR and MS. The in vitro antibacterial evaluation revealed that most of the synthesized harmine derivatives displayed better antibacterial activities against Gram-positive...

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Bibliographic Details
Main Authors: Yan Liang, Dian He, Deshun Zhou, Junshuai Li, Lei Tang, Zhen Wang
Format: Article
Language:English
Published: MDPI AG 2021-08-01
Series:Molecules
Subjects:
Online Access:https://www.mdpi.com/1420-3049/26/16/4842