Hypomethylation of the c-myc promoter region induced by phenobarbital in rat liver
Background. The changes in DNA methylation are considered as one of the early events in hepatocarcinogenesis. Objective. We evaluated the ability of phenobarbital (PB) – the most widely used anticonvulsant worldwide and classical rodent liver carcinogen – to cause the promoter region of the c-myc p...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
National Institute of Public Health - National Institute of Hygiene
2018-11-01
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| Series: | Roczniki Panstwowego Zakladu Higieny |
| Subjects: | |
| Online Access: | http://wydawnictwa.pzh.gov.pl/roczniki_pzh/pobierz-artykul?id=1251 |