Valproic acid exerts an anti-tumor effect on tongue cancer sas cells in vitro and in vivo

Valproic acid exerts an anti-tumor effect on tongue cancer sas cells in vitro and in vivo

Background: Valproic acid (VPA) is a drug approved by the Food and Drug Administration for epilepsy and bipolar disorders. It is also a known histone deacetylase inhibitor and has been evaluated as an anti-cancer agent. However, the in vitro and in vivo anti-tumor effect of VPA on human tongue cance...

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Bibliographic Details
Main Authors: Gu-Jiun Lin, Shu-Sheng Kao Chen, Shing-Hwa Huang, I-Hsun Li, Li-Chen Yen, Jang-Yi Chen, Huey-Kang Sytwu, Yuan-Wu Chen
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2015-01-01
Series:Journal of Medical Sciences
Subjects:
Valproic acid
oral squamous cell carcinoma
human tongue cancer
cell cycle
apoptosis
Online Access:http://jms.ndmctsgh.edu.tw/article.asp?issn=1011-4564;year=2015;volume=35;issue=1;spage=28;epage=36;aulast=Lin

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http://jms.ndmctsgh.edu.tw/article.asp?issn=1011-4564;year=2015;volume=35;issue=1;spage=28;epage=36;aulast=Lin

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