Comparative efficacy of 177Lu and 90Y for anti-CD20 pretargeted radioimmunotherapy in murine lymphoma xenograft models.

Comparative efficacy of 177Lu and 90Y for anti-CD20 pretargeted radioimmunotherapy in murine lymphoma xenograft models.

Pretargeted radioimmunotherapy (PRIT) is a multi-step method of selectively delivering high doses of radiotherapy to tumor cells while minimizing exposure to surrounding tissues. Yttrium-90 (90Y) and lutetium-177 (177Lu) are two of the most promising beta-particle emitting radionuclides used for rad...

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Bibliographic Details
Main Authors: Sofia H L Frost, Shani L Frayo, Brian W Miller, Johnnie J Orozco, Garrett C Booth, Mark D Hylarides, Yukang Lin, Damian J Green, Ajay K Gopal, John M Pagel, Tom A Bäck, Darrell R Fisher, Oliver W Press
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4364776?pdf=render

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http://europepmc.org/articles/PMC4364776?pdf=render

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