Magnetic resonance Q mapping reveals a decrease in microvessel density in the arcAβ mouse model of cerebral amyloidosis

Magnetic resonance Q mapping reveals a decrease in microvessel density in the arcAβ mouse model of cerebral amyloidosis

Alterations in density and morphology of the cerebral microvasculature have been reported to occur in Alzheimer`s disease patients and animal models of the disease. In this study we compared magnetic resonance imaging (MRI) techniques for their utility to detect age-dependent changes of the cerebral...

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Bibliographic Details
Main Authors: Giovanna eIelacqua, Felix eSchlegel, Martina eFüchtemeier, Jael eXandry, Markus eRudin, Jan eKlohs
Format: Article
Language:English
Published: Frontiers Media S.A. 2016-01-01
Series:Frontiers in Aging Neuroscience
Subjects:
Cerebral Amyloid Angiopathy
cerebral amyloidosis
Alzheimer`s Disease
superparamagnetic iron oxide nanoparticles
Microvessel density
dynamic susceptibilty contrast MRI
Online Access:http://journal.frontiersin.org/Journal/10.3389/fnagi.2015.00241/full

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http://journal.frontiersin.org/Journal/10.3389/fnagi.2015.00241/full

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