Design, synthesis, and bio-evaluation of new isoindoline-1,3-dione derivatives as possible inhibitors of acetylcholinesterase

Background and purpose: Alzheimer’s disease is considered one of the lead causes of elderly death around the world. A significant decrease in acetylcholine level in the brain is common in most patients with Alzheimer’s disease, therefore acetylcholinesterase (AChE) inhibitors such as donepezil and r...

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Bibliographic Details
Main Authors: Motahareh Hassanzadeh, Farshid Hassanzadeh, Ghadam Ali khodarahmi, Mahbobe Rostami, Fateme Azimi, Hamid Nadri, Farshad Homayouni Moghadam
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2021-01-01
Series:Research in Pharmaceutical Sciences
Subjects:
Online Access:http://www.rpsjournal.net/article.asp?issn=1735-5362;year=2021;volume=16;issue=5;spage=482;epage=492;aulast=Hassanzadeh