One-step Selective Synthesis of 13-epi-manoyl Oxide

The selective one-step synthesis of 13-epi-manoyl oxide is reported based on a low-temperature superacidic cyclization of sclareol. The reaction conditions have been finely tuned in order to achieve a 9:1 ratio between epimeric oxides in favor of the desired 13-epi-oxide.

Bibliographic Details
Main Authors: Olga Morarescu, Marionela Traistari, Alic Barba, Gheorghe Duca, Nicon Ungur, Veaceslav Kulcițki
Format: Article
Language:English
Published: Academy of Sciences of Moldova, Institute of Chemistry 2021-07-01
Series:Chemistry Journal of Moldova: General, Industrial and Ecological Chemistry
Subjects:
Online Access: http://www.cjm.asm.md/sites/default/files/article_files/ChemJMold_10.19261cjm.2021.820-Kulcitki.pdf