Metabolic Reprogramming of Mammary Epithelial Cells during TGF-β-Induced Epithelial-to-Mesenchymal Transition

The cytokine transforming growth factor-β (TGF-β) can induce normal breast epithelial cells to take on a mesenchymal phenotype, termed epithelial-to-mesenchymal transition (EMT). While the transcriptional and proteomic changes during TGF-β-induced EMT have been described, the metabolic rewiring that...

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Bibliographic Details
Main Authors: Wan Hua, Sarantos Kostidis, Oleg Mayboroda, Martin Giera, Marten Hornsveld, Peter ten Dijke
Format: Article
Language:English
Published: MDPI AG 2021-09-01
Series:Metabolites
Subjects:
Online Access:https://www.mdpi.com/2218-1989/11/9/626