An approach to pathway reconstruction using whole genome metabolic models and sensitive sequence searching

Metabolic models have the potential to impact on genome annotation and on the interpretation of gene expression and other high throughput genome data. The genome of Streptomyces coelicolor genome has been sequenced and some 30% of the open reading frames (ORFs) lack any functional annotation. A rece...

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Bibliographic Details
Main Authors: Saqi Mansoor, Dobson Richard Jb., Kraben Preben, Hodgson David A., Wild David L.
Format: Article
Language:English
Published: De Gruyter 2009-03-01
Series:Journal of Integrative Bioinformatics
Online Access:https://doi.org/10.2390/biecoll-jib-2009-107