Selective Interactions of Valeriana officinalis Extracts and Valerenic Acid with [3H]Glutamate Binding to Rat Synaptic Membranes

Although GABA neurotransmission has been suggested as a mechanism for Valeriana officinalis effects, CNS depression can also be evoked by inhibition of ionotropic (iGluR) and metabotropic glutamate receptors (mGluR). In this study, we examined if aqueous valerian extract interacted with glutamaterg...

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Bibliographic Details
Main Authors: Lisa M. Del Valle-Mojica, Yoshira M. Ayala-Marín, Carmen M. Ortiz-Sanchez, Bianca A. Torres-Hernández, Safa Abdalla-Mukhaimer, José G. Ortiz
Format: Article
Language:English
Published: Hindawi Limited 2011-01-01
Series:Evidence-Based Complementary and Alternative Medicine
Online Access:http://dx.doi.org/10.1155/2011/403591