A Role for Dystonia-Associated Genes in Spinal GABAergic Interneuron Circuitry

A Role for Dystonia-Associated Genes in Spinal GABAergic Interneuron Circuitry

Spinal interneurons are critical modulators of motor circuit function. In the dorsal spinal cord, a set of interneurons called GABApre presynaptically inhibits proprioceptive sensory afferent terminals, thus negatively regulating sensory-motor signaling. Although deficits in presynaptic inhibition h...

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Bibliographic Details
Main Authors: Juliet Zhang, Jarret A.P. Weinrich, Jeffrey B. Russ, John D. Comer, Praveen K. Bommareddy, Richard J. DiCasoli, Christopher V.E. Wright, Yuqing Li, Peter J. van Roessel, Julia A. Kaltschmidt
Format: Article
Language:English
Published: Elsevier 2017-10-01
Series:Cell Reports
Subjects:
spinal cord
neuronal circuitry
inhibitory interneuron
GABApre neuron
synapses
Klhl14
Tor1a
dystonia
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124717313840

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http://www.sciencedirect.com/science/article/pii/S2211124717313840

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