Multipotent cancer stem cells derived from human malignant peritoneal mesothelioma promote tumorigenesis.

During the progression of malignant peritoneal mesothelioma (MPeM), tumor nodules propagate diffusely within the abdomen and tumors are characterized by distinct phenotypic sub-types. Recent studies in solid organ cancers have shown that cancer stem cells (CSCs) play a pivotal role in the initiation...

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Bibliographic Details
Main Authors: Sheelu Varghese, Rebecca Whipple, Stuart S Martin, H Richard Alexander
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3532216?pdf=render