Therapeutic Opportunities of Interleukin-33 in the Central Nervous System

Therapeutic Opportunities of Interleukin-33 in the Central Nervous System

Interleukin-33 (IL-33), a member of the IL-1 cytokine family, is involved in various diseases. IL-33 exerts its effects via its heterodimeric receptor complex, which comprises suppression of tumorigenicity 2 (ST2) and the IL-1 receptor accessory protein (IL-1RAP). Increasing evidence has demonstrate...

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Bibliographic Details
Main Authors: Yun Sun, Yankai Wen, Luxi Wang, Liang Wen, Wendong You, Shuang Wei, Lin Mao, Hao Wang, Zuobing Chen, Xiaofeng Yang
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-05-01
Series:Frontiers in Immunology
Subjects:
interleukin-33
ST2
multiple sclerosis
ischemic stroke
trauma
hemorrhage
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2021.654626/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2021.654626/full

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