Network pharmacology identifies IL6 as an important hub and target of tibolone for drug repurposing in traumatic brain injury
Traumatic brain injury (TBI) is characterized by a complex network of signals mediating inflammatory, proliferative and apoptotic processes during its acute and chronic phases. Current therapies mitigate damage and are mainly for palliative care and there are currently no effective therapies for sec...
Main Authors: | Andrew J. McGovern, George E. Barreto |
---|---|
Format: | Article |
Language: | English |
Published: |
Elsevier
2021-08-01
|
Series: | Biomedicine & Pharmacotherapy |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S0753332221005515 |
Similar Items
-
Effects of tibolone on markers of bone metabolic activity in postmenopausal women
by: Marić-Krejović Snežana, et al.
Published: (2012-01-01) -
Astrocytes mediate the neuroprotective effects of Tibolone following brain injury
by: Luis Miguel Garcia-Segura, et al.
Published: (2015-04-01) -
Non-conventional hormone therapy - Tissue-specific Tibolone-Caution
by: Jyotsna Potdar
Published: (2010-01-01) -
Effects of Tibolone on the Breast of Postmenopausal Women
by: Peng-Hui Wang, et al.
Published: (2007-06-01) -
Comparative Efficacy of Tibolone and Classic HRT on the Urinary Complications in Menopausal Women
by: R Maasoumi, et al.
Published: (2011-01-01)