Network pharmacology identifies IL6 as an important hub and target of tibolone for drug repurposing in traumatic brain injury

Traumatic brain injury (TBI) is characterized by a complex network of signals mediating inflammatory, proliferative and apoptotic processes during its acute and chronic phases. Current therapies mitigate damage and are mainly for palliative care and there are currently no effective therapies for sec...

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Bibliographic Details
Main Authors: Andrew J. McGovern, George E. Barreto
Format: Article
Language:English
Published: Elsevier 2021-08-01
Series:Biomedicine & Pharmacotherapy
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S0753332221005515