Jiang Tang Xiao Ke Granule Play an Anti-diabetic Role in Diabetic Mice Pancreatic Tissue by Regulating the mRNAs and MicroRNAs Associated with PI3K-Akt Signaling Pathway

Jiang Tang Xiao Ke Granule Play an Anti-diabetic Role in Diabetic Mice Pancreatic Tissue by Regulating the mRNAs and MicroRNAs Associated with PI3K-Akt Signaling Pathway

Purpose: To investigate the effect of JTXK granule on the expression pattern of miRNA in pancreatic tissue of KKAy diabetic mice, and to explore the molecular mechanism and pathways of JTXK granule in anti-diabetic effect.Methods: We used high fat diet (HFD) to induce the KKAy diabetic mice and scre...

Full description

Bibliographic Details
Main Authors: Fang-Fang Mo, Tian An, Zi-Jian Zhang, Yu-Fei Liu, Hai-Xia Liu, Yan-Yun Pan, Jia-Nan Miao, Dan-Dan Zhao, Xiu-Yan Yang, Dong-Wei Zhang, Guang-Jian Jiang, Si-Hua Gao
Format: Article
Language:English
Published: Frontiers Media S.A. 2017-11-01
Series:Frontiers in Pharmacology
Subjects:
Jiang Tang Xiao Ke Granule
KK-Ay diabetic mice
Pancreas tissue
microRNA
INS-1 cell
Online Access:http://journal.frontiersin.org/article/10.3389/fphar.2017.00795/full

Internet

http://journal.frontiersin.org/article/10.3389/fphar.2017.00795/full

Similar Items