Sex Differences in Nociceptin/Orphanin FQ Peptide Receptor-Mediated Pain and Anxiety Symptoms in a Preclinical Model of Post-traumatic Stress Disorder

Sex Differences in Nociceptin/Orphanin FQ Peptide Receptor-Mediated Pain and Anxiety Symptoms in a Preclinical Model of Post-traumatic Stress Disorder

Nociceptin/Orphanin FQ (N/OFQ) is a neuropeptide that modulates pain transmission, learning/memory, stress, anxiety, and fear responses via activation of the N/OFQ peptide (NOP or ORL1) receptor. Post-traumatic stress disorder (PTSD) is an anxiety disorder that may arise after exposure to a traumati...

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Bibliographic Details
Main Authors: Yong Zhang, Ian Schalo, Cindy Durand, Kelly M. Standifer
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-01-01
Series:Frontiers in Psychiatry
Subjects:
allodynia
hyperalgesia
NOP receptor
PTSD
sex differences
single prolonged stress
Online Access:https://www.frontiersin.org/article/10.3389/fpsyt.2018.00731/full

Internet

https://www.frontiersin.org/article/10.3389/fpsyt.2018.00731/full

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