MCM3AP-AS1 KD Inhibits Proliferation, Invasion, and Migration of PCa Cells via DNMT1/DNMT3 (A/B) Methylation-Mediated Upregulation of NPY1R

MCM3AP-AS1 KD Inhibits Proliferation, Invasion, and Migration of PCa Cells via DNMT1/DNMT3 (A/B) Methylation-Mediated Upregulation of NPY1R

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Prostate cancer (PCa) is a heterogeneous tumor that commonly occurs among males worldwide. This study explored the potential role that long non-coding RNA MCM3AP antisense RNA 1 (MCM3AP-AS1) plays in PCa progression, and investigated its mechanism. MCM3AP-AS1 and neuropeptide Y receptor Y1 (NPY1R) e...

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Bibliographic Details
Main Authors: Xin Li, Jiancheng Lv, Shuai Liu
Format: Article
Language:English
Published: Elsevier 2020-06-01
Series:Molecular Therapy: Nucleic Acids
Subjects:
long non-coding RNA MCM3AP-AS1
DNA methyltransferase
neuropeptide Y receptor Y1
MAPK pathway
prostate cancer
proliferation
Online Access:http://www.sciencedirect.com/science/article/pii/S2162253120300512

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http://www.sciencedirect.com/science/article/pii/S2162253120300512

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