Somatic Mutation Profiling in Premalignant Lesions of Vulvar Squamous Cell Carcinoma

Somatic Mutation Profiling in Premalignant Lesions of Vulvar Squamous Cell Carcinoma

Vulvar squamous cell carcinoma (VSCC) originates from the progression of either a high-grade squamous intraepithelial lesion (HSIL) or differentiated-type vulvar intraepithelial neoplasia (dVIN), often in a background of <i>lichen sclerosus</i> (LS). The mechanisms leading to the progres...

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Bibliographic Details
Main Authors: Sebastian Zięba, Anne-Floor W. Pouwer, Artur Kowalik, Kamil Zalewski, Natalia Rusetska, Elwira Bakuła-Zalewska, Janusz Kopczyński, Johanna M. A. Pijnenborg, Joanne A. de Hullu, Magdalena Kowalewska
Format: Article
Language:English
Published: MDPI AG 2020-07-01
Series:International Journal of Molecular Sciences
Subjects:
vulvar squamous cell carcinoma
HSIL
dVIN
<i>lichen sclerosus</i>
HPV
NGS
Online Access:https://www.mdpi.com/1422-0067/21/14/4880

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https://www.mdpi.com/1422-0067/21/14/4880

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