Ischemia/Reperfusion Injury Revisited: An Overview of the Latest Pharmacological Strategies

Ischemia/Reperfusion Injury Revisited: An Overview of the Latest Pharmacological Strategies

Ischemia/reperfusion injury (IRI) permeates a variety of diseases and is a ubiquitous concern in every transplantation proceeding, from whole organs to modest grafts. Given its significance, efforts to evade the damaging effects of both ischemia and reperfusion are abundant in the literature and the...

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Bibliographic Details
Main Authors: Ricardo O. S. Soares, Daniele M. Losada, Maria C. Jordani, Paulo Évora, Orlando Castro-e-Silva
Format: Article
Language:English
Published: MDPI AG 2019-10-01
Series:International Journal of Molecular Sciences
Subjects:
ischemia/reperfusion injury
pro-survival pathways
mitochondria
reactive oxygen species
inflammation
risk pathway
safe pathway
cyclic guanosine 3′,5′-monophosphate/protein kinase g pathway
Online Access:https://www.mdpi.com/1422-0067/20/20/5034

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https://www.mdpi.com/1422-0067/20/20/5034

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