Computational Nanoscopy of Tight Junctions at the Blood–Brain Barrier Interface

The selectivity of the blood−brain barrier (BBB) is primarily maintained by tight junctions (TJs), which act as gatekeepers of the paracellular space by blocking blood-borne toxins, drugs, and pathogens from entering the brain. The BBB presents a significant challenge in designing neurothe...

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Bibliographic Details
Main Authors: Nandhini Rajagopal, Flaviyan Jerome Irudayanathan, Shikha Nangia
Format: Article
Language:English
Published: MDPI AG 2019-11-01
Series:International Journal of Molecular Sciences
Subjects:
Online Access:https://www.mdpi.com/1422-0067/20/22/5583