Computational Nanoscopy of Tight Junctions at the Blood–Brain Barrier Interface
The selectivity of the blood−brain barrier (BBB) is primarily maintained by tight junctions (TJs), which act as gatekeepers of the paracellular space by blocking blood-borne toxins, drugs, and pathogens from entering the brain. The BBB presents a significant challenge in designing neurothe...
Main Authors: | , , |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2019-11-01
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Series: | International Journal of Molecular Sciences |
Subjects: | |
Online Access: | https://www.mdpi.com/1422-0067/20/22/5583 |