PTP1B Inhibitory and Anti-Inflammatory Effects of Secondary Metabolites Isolated from the Marine-Derived Fungus Penicillium sp. JF-55

PTP1B Inhibitory and Anti-Inflammatory Effects of Secondary Metabolites Isolated from the Marine-Derived Fungus Penicillium sp. JF-55

Protein tyrosine phosphatase 1B (PTP1B) plays a major role in the negative regulation of insulin signaling, and is thus considered as an attractive therapeutic target for the treatment of diabetes. Bioassay-guided investigation of the methylethylketone extract of marine-derived fungus Penicillium sp...

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Bibliographic Details
Main Authors:	Youn-Chul Kim, Hyuncheol Oh, Jong Seog Ahn, Myeong-Suk Kang, Jae Hak Sohn, Kyoung-Su Kim, Dong-Sung Lee, Jae-Hyuk Jang, Wonmin Ko
Format:	Article
Language:	English
Published:	MDPI AG 2013-04-01
Series:	Marine Drugs
Subjects:	Penicillium sp. marine-derived fungi PTP1B inhibitors anti-inflammatory effect heme oxygenase-1
Online Access:	http://www.mdpi.com/1660-3397/11/4/1409

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