PTP1B Inhibitory and Anti-Inflammatory Effects of Secondary Metabolites Isolated from the Marine-Derived Fungus Penicillium sp. JF-55

PTP1B Inhibitory and Anti-Inflammatory Effects of Secondary Metabolites Isolated from the Marine-Derived Fungus Penicillium sp. JF-55

Protein tyrosine phosphatase 1B (PTP1B) plays a major role in the negative regulation of insulin signaling, and is thus considered as an attractive therapeutic target for the treatment of diabetes. Bioassay-guided investigation of the methylethylketone extract of marine-derived fungus Penicillium sp...

Full description

Bibliographic Details
Main Authors: Youn-Chul Kim, Hyuncheol Oh, Jong Seog Ahn, Myeong-Suk Kang, Jae Hak Sohn, Kyoung-Su Kim, Dong-Sung Lee, Jae-Hyuk Jang, Wonmin Ko
Format: Article
Language:English
Published: MDPI AG 2013-04-01
Series:Marine Drugs
Subjects:
Penicillium sp.
marine-derived fungi
PTP1B inhibitors
anti-inflammatory effect
heme oxygenase-1
Online Access:http://www.mdpi.com/1660-3397/11/4/1409

Internet

http://www.mdpi.com/1660-3397/11/4/1409

Similar Items